Dr. Nirmala Gonsalves and Dr. Gary Falk discussed various aspects of diagnosing and treating eosinophilic esophagitis (EoE) during a panel discussion. They addressed questions about biopsy practices, dilation approaches, and the overlap between EoE and gastroesophageal reflux disease (GERD). Dr. Falk emphasized starting dilation conservatively and using a “start low and go slow” approach, while Dr. Gonsalves highlighted the importance of careful monitoring during dilation to prevent damage. They also discussed how EoE presentations may have evolved over time, potentially due to increased awareness and improved diagnostic tools. The panelists agreed that treating inflammation first can help assess the effectiveness of dilation and that patients with EoE and motility disorders require careful clinical assessment to distinguish between the two conditions.